Who Should Not Take Tadalafil? A Doctor’s Perspective

Home » Who Should Not Take Tadalafil? A Doctor’s Perspective

Who Should Not Take Tadalafil? A Doctor’s Perspective

Posted on March 19, 2025
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Tadalafil, most well-known as Cialis, is one of the most popular medicines for erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and sometimes even pulmonary hypertension. It works effectively for millions of men around the world and is renowned for its longevity. However, there are certain health conditions and situations in people that make the use of tadalafil potentially risky or outright dangerous.
Below are seven categories of people who should steer clear of this medication unless supervised by a healthcare professional.

People on Nitrate Medications

People using rubreto, for the chest pain known as angina, should not take tadalafil. Both these medications can lower blood pressure too much and taking them in conjunction can lead to some fainting spells, heart attacks, and worse. The problem does not end there. Simply switching or skipping doses is not safe and professional medical help is paramount.

Those with Severe Heart Conditions

Severe heart issues are included but not limited to: a recent heart attack (90 days or less), stroke, and advanced heart failure. These conditions certainly make the use of tadalafil a poor choice. The medication can overstrain an already weak cardiovascular system and the added sexual activity doesn’t help matters either. A full estimate of the heart is suggestive beforehand.

Individuals with Low Blood Pressure

Individuals with low blood pressure are at risk when taking erectile dysfunction medications because tadalafil causes vasodilation or relaxation of blood vessels. Hypotension, dizziness, fainting and dehydration could become problematic, especially if medications that lower blood pressure are being taken. Caution is critical here.

Treat ED, BPH, or PAH with the prescription medication of Tadalafil

Having Medical Conditions Related to the Liver or Kidney

This category includes patients with severely compromised liver disease such as cirrhosis or end-stage kidney disease. These organ processes metabolize the drug, creating the potential for bad side effects from drug accumulation in the body. Changing these doses may be within reach, but requires careful medical supervision to prevent dangers.

Anyone Allergic To Tadalafil

People with known hypersensitivity to tadalafil or other similar medications, like sildenafil, should not consider taking it. Reactions may include rashes, swelling, and even breathing problems. Signs from a previous dose, no matter how mild, should be an indication to steer clear – things can get nasty.

Men Taking Some Other ED Medication

Tadalafil should not be used in conjunction with other PDE5 inhibitors like Viagra or Levitra. Using more than one tablet for a similar aim does not yield better results; instead, it increases the likelihood of adverse effects including flushing, pain in the head, or even priapism which is a painful erection for an exceedingly long time. One at a time is the better way.

People using recreational “poppers”

“Poppers” is the term given to a class of drugs that enhance sexual urges and give a cloud-nine high to those who take them. Fun as it may sound, it shouldn’t be used with Tadalafil as it is dangerous. Like nitrates, they lower blood pressure, and the combination can have a lethal outcome. This mix needs to be avoided always. 

Final Thoughts

Many people stand to gain from using Tadalafil; however, it is not completely safe. For people from any of these seven categories there are alternatives and a qualified healthcare professional can suggest what best meets particular health requirements.
Before starting Tadalafil, one must always confide in their doctors about their medical history and the medications that they are currently on. Remember, decisions on health and well-being rest on knowledge and professional advice.

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